Grant opportunity · PAR-25-051
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Who can apply (as listed)
- State governments
- Native American tribal organizations (other than federally recognized governments)
- Native American tribal governments (federally recognized)
- Public housing authorities / Indian housing authorities
- Public and state-controlled institutions of higher education
- City or township governments
- For-profit organizations (other than small businesses)
- Others (see the opportunity text)
- County governments
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Special district governments
- Private institutions of higher education
- Small businesses
- Independent school districts
The Blueprint Neurotherapeutics Network (BPN) invites applications from neuroscience investigators seeking support to advance their small molecule drug discovery and development projects into the clinic. Participants in the BPN are responsible for conducting all studies that involve disease- or target-specific assays, models, and other research tools and receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in medicinal chemistry, pharmacokinetics, toxicology, formulations development, chemical synthesis including under Good Manufacturing Practices (GMP), and Phase I clinical testing. Projects can enter either at the Discovery stage, to optimize promising hit compounds through medicinal chemistry to the Development stage, to advance a single development candidate through Investigational New Drug (IND)…
Excerpt as published. The full synopsis, required forms, and any amendments are on the official listing.
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