Grant opportunity · PAR-25-060
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
Who can apply (as listed)
- Independent school districts
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- Public housing authorities / Indian housing authorities
- County governments
- Special district governments
- Native American tribal governments (federally recognized)
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- State governments
- Private institutions of higher education
- Others (see the opportunity text)
- Native American tribal organizations (other than federally recognized governments)
- City or township governments
- Public and state-controlled institutions of higher education
- Small businesses
- For-profit organizations (other than small businesses)
This funding opportunity announcement (FOA) encourages the development and validation of animal models and human/animal tissue ex vivo systems that recapitulate the phenotypic and physiologic characteristics of a defined neurological or neuromuscular disorder. The goal of this FOA is to promote a significant improvement in the translational relevance of animal models or ex vivo systems that will be utilized to facilitate future development of neurotherapeutics. Ideally, models proposed for this FOA would have the potential to provide feasible and meaningful assessments of efficacy following therapeutic intervention that would be applicable in both preclinical and clinical settings. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) Program focused on enabling the exploratory and early stages of drug discovery.
Excerpt as published. The full synopsis, required forms, and any amendments are on the official listing.
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