GrantSet

Grant opportunity · PAR-25-024

Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

Applications close526 days leftJan 7, 2028
AgencyNational Institutes of Health
CategoryDiscretionary
Assistance listing93.853,93.866
OpensOct 28, 2024
ClosesJan 7, 2028
Award floor
Award ceiling
Expected awardsNot stated

Who can apply (as listed)

  • Native American tribal governments (federally recognized)
  • City or township governments
  • State governments
  • Private institutions of higher education
  • Others (see the opportunity text)
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Public housing authorities / Indian housing authorities
  • For-profit organizations (other than small businesses)
  • Public and state-controlled institutions of higher education
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
  • Native American tribal organizations (other than federally recognized governments)
  • Small businesses
  • County governments
  • Independent school districts
  • Special district governments
From the listing

The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and/or early evaluation of strong candidate biomarkers and biomarker signatures that can be used as tools to facilitate the clinical development of neurotherapeutics and their use in clinical practice. Specifically, the focus of this FOA is on the identification and initial biological, analytical and clinical evaluation of biomarkers and biomarker signatures for neurological and neuromuscular disorders. Although research supported by this FOA can include animal studies, it must also include preliminary human evaluation using carefully standardized human samples or datasets. The goal of this initiative is to deliver candidate biomarkers or biomarker signatures that are ready for definitive analytical and clinical validation studies.

Excerpt as published. The full synopsis, required forms, and any amendments are on the official listing.

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