Grant opportunity · PAR-25-153
Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed)
Who can apply (as listed)
- Small businesses
- Independent school districts
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Special district governments
- Others (see the opportunity text)
- For-profit organizations (other than small businesses)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than federally recognized governments)
- Private institutions of higher education
- County governments
- City or township governments
- Public and state-controlled institutions of higher education
- State governments
- Native American tribal governments (federally recognized)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for identification of small molecules that function to elucidate the biology of disease as chemical probes or function as agonists or antagonists of disease target(s) for therapy or immunotherapy. The NOFO is intended to support discovery research for the identification of validated hits relevant to health-related outcomes of participating NIH Institutes. Stages of discovery research covered by this NOFO include: 1) assay development for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; 2) screen implementation high throughput target-focused approaches or moderate throughput phenotypic- and fragment-based approaches to identify in…
Excerpt as published. The full synopsis, required forms, and any amendments are on the official listing.
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