GrantSet

Grant opportunity · PAR-25-291

Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)

Applications close526 days leftJan 7, 2028
AgencyNational Institutes of Health
CategoryDiscretionary
Assistance listing93.242
OpensNov 22, 2024
ClosesJan 7, 2028
Award floor
Award ceiling$200,000
Expected awardsNot stated

Who can apply (as listed)

  • Public and state-controlled institutions of higher education
  • Native American tribal organizations (other than federally recognized governments)
  • Small businesses
  • Nonprofits without 501(c)(3) status (other than institutions of higher education)
  • Special district governments
  • For-profit organizations (other than small businesses)
  • Others (see the opportunity text)
  • State governments
  • City or township governments
  • Public housing authorities / Indian housing authorities
  • Native American tribal governments (federally recognized)
  • Private institutions of higher education
  • County governments
  • Independent school districts
  • Nonprofits with 501(c)(3) status (other than institutions of higher education)
From the listing

Reissue of RFA-20-351.The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications to pursue invasive neural recording studies focused on mental health-relevant questions. Invasive neural recordings provide an unparalleled window into the human brain to explore the neural circuitry and neural dynamics underlying complex moods, emotions, cognitive functions, and behaviors with high spatial and temporal resolution. Additionally, the ability to stimulate, via the same electrodes, allows for direct causal tests by modulating network dynamics. This funding opportunity aims to target a gap in the scientific knowledge of neural circuit function related to mental health disorders. Researchers should target specific questions suited to invasive recording modalities that have high translational potential. Development of new technologies and therapies are outside the scope of this NOFO.

Excerpt as published. The full synopsis, required forms, and any amendments are on the official listing.

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