Grant opportunity · PAR-25-442
Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
Who can apply (as listed)
- Native American tribal organizations (other than federally recognized governments)
- For-profit organizations (other than small businesses)
- Native American tribal governments (federally recognized)
- City or township governments
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- County governments
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Special district governments
- Public housing authorities / Indian housing authorities
- Small businesses
- Others (see the opportunity text)
- State governments
- Independent school districts
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. Applicants will identify a human disease relevant undruggable target class and develop a method or agent that is selective for one or more targets within that target class. This NOFO is intended to jumpstart research that demonstrates innovative strategies to modulate targets that cannot be addressed by established therapeutic types, furthering the development of methods and/or agents selective for undruggable target classes.
Excerpt as published. The full synopsis, required forms, and any amendments are on the official listing.
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