GrantSet

Special Notice · S-196061

TECHNOLOGY LICENSING OPPORTUNITY: SurfGraphPro

Responses due129 days leftDec 5, 2026, 5:00 PM EST
OfficeTriad - Doe Contractor
PSCAJ11
Set-asideNo Set aside used
PostedJun 5, 2026
DeadlineDec 5, 2026, 5:00 PM EST
Place of performanceLos Alamos, NM, 87545
From the notice

SurfGraphPro, an AI tool, transforms complex protein structures into an easy-to-analyze format that helps researchers quickly identify binding sites, predict molecular interactions and understand protein behavior with greater speed and scalability than traditional approaches. By combining 3D surface graph representations with advanced machine learning, this technology from Los Alamos National Laboratory reduces the computational burden of protein analysis while preserving the structural detail needed for high-value applications in drug discovery, antibody design, pathogen detection and custom protein engineering. The Challenge: Protein surfaces are extremely complex, three-dimensional structures, and that complexity makes them difficult to analyze using traditional computational approaches. In practice, many existing methods rely on hand-selected biochemical features, expensive calculations or narrow task-specific models that do not generalize well to new questions. As a result, resea…

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